Eyes Wide Shut: A Cohort Study Questioning the Role of Fundoscopy in Infective Endocarditis Diagnosis

Clin Infect Dis. 2024 Mar 20;78(3):663-666. doi: 10.1093/cid/ciae067.


In this retrospective/prospective study, we assessed the role of fundoscopy in 711 episodes with suspected infective endocarditis (IE); 238 (33%) had IE. Ocular embolic events (retinal emboli or chorioretinitis/endophthalmitis) and Roth spots were found in 37 (5%) and 34 (5%) episodes, respectively, but had no impact on IE diagnosis.

Keywords: Duke criteria; Roth spots; fundoscopy; infective endocarditis; ocular embolic events.

MeSH terms

  • Cohort Studies
  • Embolism*
  • Endocarditis* / diagnosis
  • Endocarditis, Bacterial* / diagnostic imaging
  • Humans
  • Prospective Studies
  • Retrospective Studies