Abstract
Leigh's disease is a subacute metabolic encephalopathy characterized by bilateral and symmetrical lesions of basal ganglia, mid-brain and pons. Lesions are related to an abnormal pyruvate metabolism which mechanisms remain still uncertain. This disease is rare and the authors present a case with complete anatomic study.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Brain / metabolism
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Brain / pathology*
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Brain Diseases, Metabolic / pathology*
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Child, Preschool
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Humans
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Leigh Disease / pathology*
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Male
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Mitochondria, Heart / ultrastructure
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Myocardium / pathology*
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Myocardium / ultrastructure
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Pyruvates / metabolism
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Pyruvic Acid