Continuous in situ targeted antibiotics for late cardiovascular implantable electronic device pocket perforation

J Arrhythm. 2023 Dec 8;40(1):170-173. doi: 10.1002/joa3.12972. eCollection 2024 Feb.

Abstract

CIED infections are a dreaded complication associated with significant morbidity and mortality and the mainstay of treatment has traditionally been extraction. A recent cohort study suggested that continuous, in situ-targeted, ultrahigh concentrations of antibiotics (CITA) delivered into the CIED pocket may be a viable alternative to extraction in selected cases. We highlight two cases of device perforation which were successfully treated with this technique.

Keywords: CIED extraction; CIED infection; CITA; Pocket infection.