In Vivo Porcine Model of Acute Iliocaval Deep Vein Thrombosis

J Endovasc Ther. 2024 Feb 15:15266028241231513. doi: 10.1177/15266028241231513. Online ahead of print.


The study establishes a rapid, technically straightforward, and reproducible porcine large animal model for acute iliocaval deep vein thrombosis (DVT). The procedure can be performed with basic endovascular skillsets. With its procedural efficiency and consistency, the platform is promising for comparative in vivo testing of venous thrombectomy devices in a living host, and for future verification and validation studies to determine efficacy of novel thrombectomy devices relative to predicates.

Keywords: balloon occlusion; deep vein thrombosis; iliocaval; large animal model; venous thrombectomy.