Low-grade Appendiceal Mucinous Neoplasm with Appendiceal Reduction and Re-expansion Over a Two-year Period

Intern Med. 2024 Sep 15;63(18):2519-2523. doi: 10.2169/internalmedicine.3136-23. Epub 2024 Feb 19.

Abstract

A 71-year-old woman was found to have submucosal tumor-like lesion on colonoscopy (CS) before gastric surgery, and computed tomography (CT) showed a 12-mm structure at the base of the appendix. The lesion could not be clearly detected on CT nine months later, but it had enlarged again on CT one year later; therefore, CS and endoscopic ultrasound (EUS) were performed. The lesion was determined to be cystic with viscous contents, and laparoscopic appendicectomy was performed. This is the first report of low-grade appendiceal mucinous neoplasm (LAMN) diagnosed by a histopathologic examination of a resected specimen showing shrinkage and re-expansion of the appendix.

Keywords: LAMN; appendiceal tumor; mucocele; re-expansion of appendix; shrinkage of appendix.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Mucinous* / diagnostic imaging
  • Adenocarcinoma, Mucinous* / pathology
  • Adenocarcinoma, Mucinous* / surgery
  • Aged
  • Appendectomy*
  • Appendiceal Neoplasms* / diagnostic imaging
  • Appendiceal Neoplasms* / pathology
  • Appendiceal Neoplasms* / surgery
  • Appendix / diagnostic imaging
  • Appendix / pathology
  • Appendix / surgery
  • Colonoscopy
  • Female
  • Humans
  • Laparoscopy
  • Neoplasm Grading
  • Time Factors
  • Tomography, X-Ray Computed