Comparison of narrow band imaging versus white light imaging in detecting non muscle invasive bladder cancer

Urologia. 2024 May;91(2):289-297. doi: 10.1177/03915603241232115. Epub 2024 Feb 19.


Background: In the present study, we compared Narrow Band Imaging (NBI) and White Light Cystoscopy (WLC) in Non-muscle invasive bladder cancer (NMIBC) for detection and its impact on recurrence.

Materials and methods: This prospective study was conducted in the department of Urology at a tertiary institution from August 2021 to April 2023. The main aim was to determine the benefit of addition of NBI during TURBT in NMIBC. All patients with Urinary Bladder Mass (size less than 5 cm on USG/CT) aged >18 years of age planned for TURBT were included.

Results: Amongst 63 patients, the mean age was 59.84 ± 11.3 years; 80% were males. Sixty percent of patients had history of Tobacco consumption and Type II DM was the most common comorbidity (59%). Commonest symptom was gross haematuria. Posterior wall was most commonly involved and papillary lesions were commonest. A total of 125 lesions were identified on WLI, with mean 1.98 ± 1.75 and 78 additional lesions were identified only on NBI with mean 1.24 ± 1.63 lesions. Four patients had intra-operative complications. Five patients had recurrence at 6 weeks and eight patients had recurrence at 3 months. NBI had detected more lesions in patients who developed recurrence at 6 weeks and 3 months (mean: 1.41 and 1.43).

Conclusion: NBI has additive role in detecting NMIBC lesions missed on WLI. NBI has significant role in preventing recurrence at 3 months and more so by detecting high grade tumours.

Keywords: Bladder malignancy; detection; narrow band imaging; recurrence; white light cystoscopy.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cystoscopy*
  • Female
  • Humans
  • Light
  • Male
  • Middle Aged
  • Narrow Band Imaging* / methods
  • Neoplasm Invasiveness*
  • Prospective Studies
  • Urinary Bladder Neoplasms* / diagnostic imaging
  • Urinary Bladder Neoplasms* / pathology