Accuracy of intraocular lens formulas in combined phacovitrectomy

Chanon Thanitcul; Abdelhalim A Awidi; John G Ladas; Aazim A Siddiqui; Christina R Prescott; Kraig S Bower; Albert S Jun; Yassine Daoud; Divya Srikumaran

doi:10.1007/s10792-024-03019-7

Accuracy of intraocular lens formulas in combined phacovitrectomy

Int Ophthalmol. 2024 Feb 19;44(1):96. doi: 10.1007/s10792-024-03019-7.

Authors

Chanon Thanitcul¹, Abdelhalim A Awidi¹, John G Ladas^{1

2}, Aazim A Siddiqui³, Christina R Prescott⁴, Kraig S Bower¹, Albert S Jun¹, Yassine Daoud^{5

6}, Divya Srikumaran^{7

8}

Affiliations

¹ Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
² Maryland Eye Consultants and Surgeons, Silver Spring, MD, 20902, USA.
³ Solomon Eye Physicians and Surgeons, Bowie, MD, 20716, USA.
⁴ NYU Langone Eye Center, NYU Grossman School of Medicine, New York, NY, 10017, USA.
⁵ Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. ydaoud1@jhmi.edu.
⁶ Cornea, Cataract, and Refractive Surgery Services, Maumenee 327, Wilmer Eye Institute, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD, 21287, USA. ydaoud1@jhmi.edu.
⁷ Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. dsrikum1@jhmi.edu.
⁸ , 1106 Annapolis Road, Suite 290, Odenton, MD, 21113, USA. dsrikum1@jhmi.edu.

PMID: 38372824
DOI: 10.1007/s10792-024-03019-7

Abstract

Purpose: To assess the refractive accuracy of eight intraocular lens (IOL) formulas in eyes that underwent combined phacovitrectomy.

Methods: A retrospective chart review of 59 eyes that underwent uncomplicated phacovitrectomy between 2017 and 2020 at the Johns Hopkins Wilmer Eye Institute. Inclusion criteria were postoperative best corrected visual acuity of 20/40 or better within 6 months of surgery and IOL implantation in the capsular bag. The Barrett Universal II (BUII), Emmetropia Verifying Optical (EVOv2.0), Hill-Radial Basis Function (Hill-RBFv3.0), Hoffer Q, Holladay I, Kane, Ladas Super Formula (LSF), and SRK/T formulas were compared for accuracy in predicting postoperative spherical equivalents (SE) using Wilcoxon rank sum tests. Pearson's correlation coefficients were used to assess correlations between biometric parameters and errors for all formulas.

Results: Prediction errors of SE ranged from - 1.69 to 1.43 diopters (D), mean absolute errors (MAE) ranged from 0.39 to 0.47 D, and median absolute errors (MedAE) ranged from 0.23 to 0.37 D among all formulas. The BUII had the lowest mean error (- 0.043), MAE (0.39) and MedAE (0.23). The BUII also had the highest percentage of eyes with predicted error within ± 0.25 D (51%) and ± 0.50 D (83%). Based on MedAE however, no pairwise comparisons resulted in statistically significant differences. Axial length (AL) was positively correlated with the error from the Hoffer Q and Holladay I formulas (correlation coefficients = 0.34, 0.30, p values < 0.01, 0.02 respectively).

Conclusion: While all eight IOL formulas had comparable accuracy in predicting refractive outcomes in eyes undergoing combined phacovitrectomy, the BUII and Kane formulas had a tendency to greater accuracy.

Keywords: Accuracy; Formulas; Intraocular lens; Phacovitrectomy.

MeSH terms

Eye
Eye, Artificial*
Humans
Lenses, Intraocular*
Refraction, Ocular
Retrospective Studies