Chemical composition and pharmacological activity of seco-prezizaane-type sesquiterpenes

Ye Jin; Yanqing Xie; Peng Zhang; Afsar Khan; Zhihong Zhou; Lu Liu

doi:10.1016/j.chmed.2023.06.003

Chemical composition and pharmacological activity of seco-prezizaane-type sesquiterpenes

Chin Herb Med. 2023 Dec 11;16(1):70-81. doi: 10.1016/j.chmed.2023.06.003. eCollection 2024 Jan.

Authors

Ye Jin¹, Yanqing Xie¹, Peng Zhang¹, Afsar Khan², Zhihong Zhou¹, Lu Liu¹

Affiliations

¹ Yunnan Yunzhong Institute of Nutrition and Health, Yunnan University of Chinese Medicine, Kunming 650500, China.
² Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.

Abstract

The seco-prezizaane-type sesquiterpenes (SPS), as a special class of sesquiterpenes with a highly oxidative five-ring cage structure and seven consecutive chiral centers, are isolated from the genus Illicium, which have a variety of biological activities, including neurotoxicity and neurotrophic effects, etc. This review summarizes the chemical constituents and pharmacological effects of SPS, and discusses the potential trend and scope of future research.

Keywords: Illicium genus; anisatin; chemical composition; majucin; pharmacological activity; seco-prezizaane-type sesquiterpenes.

Publication types

Review