Vascular Responses to Acute Induced Inflammation With Aging: Does Fitness Matter?

Exerc Sport Sci Rev. 2024 Apr 1;52(2):68-75. doi: 10.1249/JES.0000000000000334. Epub 2024 Feb 16.

Abstract

Acute inflammation impairs vascular function in an age-dependent manner and affects cardiovascular event risk. Regular aerobic exercise preserves vascular function with aging and potentially modifies how acute inflammation affects the vasculature. We hypothesize high cardiorespiratory fitness may accompany greater arterial responsiveness post-acute inflammation in older adults.

MeSH terms

  • Aged
  • Aging / physiology
  • Cardiorespiratory Fitness* / physiology
  • Exercise / physiology
  • Humans
  • Inflammation
  • Vascular Stiffness* / physiology