Effect of repetitive transcranial magnetic stimulation-assisted training on lower limb motor function in children with hemiplegic cerebral palsy

BMC Pediatr. 2024 Feb 22;24(1):136. doi: 10.1186/s12887-024-04605-5.

Abstract

Objective: To explore the effect of repetitive transcranial magnetic stimulation (rTMS)-assisted training on lower limb motor function in children with hemiplegic cerebral palsy (HCP).

Method: Thirty-one children with HCP who met the inclusion criteria were selected and randomly divided into a control group (n = 16) and an experimental group (n = 15). The control group received routine rehabilitation treatment for 30 min each time, twice a day, 5 days a week for 4 weeks. Based on the control group, the experimental group received rTMS for 20 min each time, once a day, 5 days a week for 4 weeks. The outcome measures included a 10-metre walk test (10MWT), a 6-minute walk distance (6MWD) test, D- and E-zone gross motor function measurements (GMFM), the symmetry ratio of the step length and stance time and the muscle tone of the triceps surae and the hamstrings (evaluated according to the modified Ashworth scale), which were obtained in both groups of children before and after treatment.

Results: After training, the 10MWT (P < 0.05), 6MWD (P < 0.01), GMFM (P < 0.001) and the symmetry ratio of the step length and stance time of the two groups were significantly improved (P < 0.05), there was more of an improvement in the experimental group compared with the control group. There was no significant change in the muscle tone of the hamstrings between the two groups before and after treatment (P > 0.05). After treatment, the muscle tone of the triceps surae in the experimental group was significantly reduced (P < 0.05), but there was no significant change in the control group (P > 0.05).

Conclusion: Repetitive TMS-assisted training can improve lower limb motor function in children with HCP.

Keywords: Hemiplegic cerebral palsy; Lower limb; Motor function; Rehabilitation; Repetitive transcranial magnetic stimulation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Cerebral Palsy*
  • Child
  • Hemiplegia / etiology
  • Humans
  • Lower Extremity
  • Transcranial Magnetic Stimulation*
  • Walking