The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis

Affiliations

• ¹ School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA. l.m.verheijen1@gmail.com.
• ² Department of Neuroscience, Maastricht University, Maastricht, The Netherlands. l.m.verheijen1@gmail.com.
• ³ School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
• ⁴ Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
• ⁵ Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
• ⁶ Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan.
• ⁷ Department of Neuropathology, Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.
• ⁸ Department of Clinical and Experimental Epilepsy, University College London Queen Square Institute of Neurology, London, WC1N 3BG, UK.
• ⁹ Chalfont Centre for Epilepsy, Chalfont St Peter, SL9 0RJ, UK.
• ¹⁰ Division of Neuropathology, Department of Brain Disease Research, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
• ¹¹ Department of Biological Sciences, Mississippi State University, Mississippi State, MS, 39762, USA.