Neurosarcoidosis with enlargement of the dorsal root ganglia: A case report

Radiol Case Rep. 2024 Feb 13;19(5):1718-1721. doi: 10.1016/j.radcr.2024.01.032. eCollection 2024 May.

Abstract

We report the case of a woman in her 40s who presented with sensory disturbances in all 4 limbs and left facial palsy. MRI revealed asymmetric enlargement of the dorsal root ganglia, which was enhanced by gadolinium-a chest CT scan identified enlarged supraclavicular, mediastinal, and hilar lymph nodes. A biopsy of a hilar lymph node showed noncaseating epithelioid granulomas, confirming a sarcoidosis diagnosis. Prednisolone treatment led to symptomatic improvements. In sarcoidosis of the peripheral nervous system, there might be observable enlargement of the dorsal root ganglion alongside enhanced gadolinium contrast. Obtaining a biopsy from the dorsal root ganglion poses challenges, and radiologists should be mindful of this specific imaging characteristic.

Keywords: Dorsal root ganglion enlargement; MRI; Neurosarcoidosis; Peripheral nervous system.

Publication types

  • Case Reports