Prevention in Hepatology

J Pers Med. 2024 Jan 23;14(2):132. doi: 10.3390/jpm14020132.

Abstract

The prevention of liver disease has improved significantly in the last few decades, to the point that it can now be considered a true success story. The wide variety of interventions, including comprehensive vaccination strategies, novel medications, lifestyle changes, and even preventive surgeries, have reduced the morbidity and mortality of chronic liver diseases. However, the prevalence of chronic liver diseases is increasing worldwide. Currently, fatty liver disease alone is estimated to be present in as much as 30% of the adult population. Furthermore, there is a trend towards increasing incidences of chronic hepatitis B, and a global lack of success in efforts to eliminate chronic hepatitis C. Thus, improving and efficiently rolling out existing and successful prevention strategies for chronic liver diseases will play an essential role in healthcare throughout the upcoming decades. In this review, we summarize the current options and concepts for preventing chronic liver diseases, highlight their limitations, and provide an outlook on probable future developments to improve awareness, integrated care, and the analysis of big data.

Keywords: hepatology; liver disease; management; prevention.

Publication types

  • Review

Grants and funding

A.T. received a grant from the Sino-German Center for Research Promotion (GZ-1546), the State Ministry of Baden-Wuerttemberg for Sciences, Research and Arts supporting the Clinical Cooperation Unit Healthy Metabolism at the Center for Preventive Medicine and Digital Health (CCU Healthy Metabolism), the Baden-Wuerttemberg Center for Digital Early Disease Detection and Prevention (BW-ZDFP) and the Federal MinistryEducation and Research (BMBF, Q-HCC, 01KD22214).