Updates on the Prevention and Management of Post-Polypectomy Bleeding in the Colon

Gastrointest Endosc Clin N Am. 2024 Apr;34(2):363-381. doi: 10.1016/j.giec.2023.09.008. Epub 2023 Sep 27.


Post-polypectomy bleeding (PPB) remains a significant procedure-related complication, with multiple risk factors determining the risk including patient demographics, polyp characteristics, endoscopist expertise, and techniques of polypectomy. Immediate PPB is usually treated promptly, but management of delayed PPB can be challenging. Cold snare polypectomy is the optimal technique for small sessile polyps with hot snare polypectomy for pedunculated and large sessile polyps. Topical hemostatic powders and gels are being investigated for the prevention and management of PPB. Further studies are needed to compare these topical agents with conventional therapy.

Keywords: Bleeding prevention; GI bleed; Polypectomy; Snare resection.

Publication types

  • Review

MeSH terms

  • Colon
  • Colonic Polyps* / surgery
  • Colonoscopy* / adverse effects
  • Colonoscopy* / methods
  • Gastrointestinal Hemorrhage* / etiology
  • Humans
  • Postoperative Hemorrhage
  • Risk Factors