Exploring patterns of alcohol use and alcohol use disorder among Asian Americans with a finer lens

Drug Alcohol Depend. 2024 Apr 1:257:111120. doi: 10.1016/j.drugalcdep.2024.111120. Epub 2024 Feb 7.

Abstract

Background: National survey data suggest Asian Americans (AA) are less likely to consume alcohol and develop AUD than Americans in other groups. However, it is common for AA to be born outside of the US and carry gene variants that alter alcohol metabolism, both of which can lead to lower levels of alcohol involvement. The current study examined differences in alcohol use and AUD between AA and other groups before and after controlling for birth location and gene variants.

Design: Past year alcohol measures were examined from adults 18+ (N=22,848) in the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions III before and after controlling for birth location (inside or outside of the US) and gene variants (ALDH2*2 and ADH1B*2/ADH1B*3). Gender gaps in alcohol measures also were assessed.

Results: Before adjustments, AA were less likely than White Americans to drink in the previous year (OR=0.50, 95% CI 0.41-0.62), binge (OR=0.68, 95% CI 0.52-0.88), engage in frequent heavy drinking (OR=0.55, 95% CI 0.42-0.73), and reach criteria for AUD (OR=0.71, 95% CI 0.53-0.94). After controlling for birth location and gene variants, AA remained less likely to drink in the past year (OR=0.54, 95% CI 0.41-0.70) but all other differences disappeared. Gender gaps were only observed for AA born outside of the US, highlighting the importance of experience rather than racial category per se.

Conclusions: Findings indicate that heterogeneity among AA leads to spurious generalizations regarding alcohol use and AUD and challenge the model minority myth.

Keywords: ADH1B; ALDH2; Acetaldehyde; Alcohol; Asian American; International birth.

MeSH terms

  • Adult
  • Alcohol Dehydrogenase
  • Alcohol Drinking / epidemiology
  • Alcohol Drinking / genetics
  • Alcoholism* / epidemiology
  • Alcoholism* / genetics
  • Aldehyde Dehydrogenase, Mitochondrial
  • Asian
  • Ethanol
  • Humans
  • White

Substances

  • Ethanol
  • Alcohol Dehydrogenase
  • Aldehyde Dehydrogenase, Mitochondrial
  • ALDH2 protein, human