Lupus Vasculitis

J Ayub Med Coll Abbottabad. 2023 Jul-Sep;35(3):475-478. doi: 10.55519/JAMC-03-10849.


We present the case of a 30-year-old woman who presented with 8-month history of intermittent fever, joint pains with morning stiffness, recurrent oral ulcers, photosensitivity, weight loss and hair fall. For the last 2 months, she had developed a dry cough with progressive shortening of breath. On examination, a cachexic lady with malar hyperpigmentation, alopecia, pallor, nail dystrophy and erythema over her hands and feet were noted. There were multiple punched-out skin ulcers of variable size over legs, arms and abdomen usually round in shape with well-defined even wound margins and scant serous discharge. Musculoskeletal examination revealed synovitis of both elbows and a few metacarpophalangeal and proximal interphalangeal joints. Chest X-ray and HRCT showed bilateral ground-glass opacification. Anti-Nuclear Antibody (ANA) was positive, 1:320, homogenous nuclear pattern. Anti-Ro antibody was highly positive and serum complement (C3, C4) levels were reduced. She was diagnosed with Lupus Vasculitis and started on steroids, mycophenolate mofetil and hydroxychloroquine.

Keywords: Systemic Lupus Erythematosus; ANA; Cutaneous Vasculitis; Pulmonary Vasculitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arthralgia
  • Female
  • Fever
  • Humans
  • Mycophenolic Acid*
  • Vasculitis*


  • Mycophenolic Acid