Gentamicin should remain part of the empirical sepsis regimen for adults

Maria Mellemstrand Grønmo; Janne Møller-Stray; Per Espen Akselsen; Paul Christoffer Lindemann; Aasmund Fostervold; Caroline Vestby Knudsen; Per Kristian Knudsen; Morten Lindbæk; Kristian Tonby; Arnfinn Sundsfjord

doi:10.4045/tidsskr.23.0659

Gentamicin should remain part of the empirical sepsis regimen for adults

Tidsskr Nor Laegeforen. 2024 Feb 26;144(3). doi: 10.4045/tidsskr.23.0659. Print 2024 Feb 27.

[Article in English, Norwegian]

Authors

Maria Mellemstrand Grønmo, Janne Møller-Stray, Per Espen Akselsen, Paul Christoffer Lindemann, Aasmund Fostervold, Caroline Vestby Knudsen, Per Kristian Knudsen, Morten Lindbæk, Kristian Tonby, Arnfinn Sundsfjord

PMID: 38415563
DOI: 10.4045/tidsskr.23.0659

No abstract available

Plain language summary

In the Norwegian guidelines, the combination of a narrow-spectrum beta-lactam antibiotic and aminoglycoside should remain the first choice for empirical antibiotic therapy for the majority of severe infections.

MeSH terms

Adult
Aminoglycosides / therapeutic use
Anti-Bacterial Agents / adverse effects
Drug Therapy, Combination
Gentamicins* / adverse effects
Humans
Sepsis* / drug therapy

Substances

Gentamicins
Anti-Bacterial Agents
Aminoglycosides