Spinal intramedullary uterine carcinosarcoma metastasis

BMJ Case Rep. 2024 Feb 27;17(2):e259268. doi: 10.1136/bcr-2023-259268.

Abstract

Intramedullary spinal cord metastases (ISCM) are a rare and challenging manifestation of metastatic cancer that have devastating impacts on the individual's neurological function, survival expectancy and overall quality of life. Given the rarity and poor prognosis, there is a lack of consensus in management. Uterine carcinosarcoma itself is a rare cancer, accounting for less than 3% of all uterine cancers. It carries a poor prognosis, with only one-third of patients surviving beyond 5 years. There are no previous reports of uterine carcinosarcoma metastases to the spinal cord. Here, we present the case of a woman in her late 70s with a uterine carcinosarcoma intramedullary metastasis that was refractory to radiotherapy treatment and responded favourably to surgical debulking.

Keywords: Cancer - see Oncology; Neurooncology; Neurosurgery; Spinal cord.

Publication types

  • Case Reports

MeSH terms

  • Carcinosarcoma* / surgery
  • Female
  • Humans
  • Quality of Life
  • Spinal Cord Neoplasms* / diagnostic imaging
  • Spinal Cord Neoplasms* / secondary
  • Spinal Cord Neoplasms* / surgery
  • Uterine Neoplasms* / surgery