Abstract
The use of serum enzymes in the detection of tissue damage due to disease or toxins is now well established but the full potential for the use of urinary enzymes to detect and monitor kidney damage has not been realized. There are a number of problems involved in dealing with urinary enzymes and these have not always been fully appreciated by research workers. This report discusses some of the difficulties and how they can be overcome.
MeSH terms
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Acetylglucosaminidase / urine
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Alkaline Phosphatase / urine
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Animals
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Drug Stability
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Enzyme Inhibitors / urine
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Enzymes / urine*
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Glutamate Dehydrogenase / urine
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Kidney Diseases / enzymology*
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L-Lactate Dehydrogenase / urine
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Male
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Muramidase / urine
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Rats
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Sex Factors
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Specimen Handling
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Time Factors
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Urine
Substances
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Enzyme Inhibitors
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Enzymes
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L-Lactate Dehydrogenase
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Glutamate Dehydrogenase
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Alkaline Phosphatase
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Muramidase
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Acetylglucosaminidase