Fusarium moniliforme was demonstrated to be the etiologic agent in an Italian case of eumycotic mycetoma. The fungus produced white granules, which measured 80 X 133 by 212 X 478 microns. Their edges were entire or lobed and were surrounded by an eosinophilic homogeneous material. The hyphae comprising the granules were not embedded in cement. The etiologic agent, first considered to be an Acremonium species, was restudied and identified as F. moniliforme on the basis that it not only produced chains of microconidia but also curved, multi-septate macroconidia typical of the genus Fusarium.