Differential Diagnosis of Autism and Other Neurodevelopmental Disorders

Pediatr Clin North Am. 2024 Apr;71(2):157-177. doi: 10.1016/j.pcl.2023.12.004. Epub 2024 Jan 5.


This article discusses the diagnostic criteria for autism spectrum disorder (ASD), as well as other neurodevelopmental disorders that may be confused with or co-occur with ASD. Practitioners involved in diagnostic assessment of ASD must be well versed in the features that differentiate ASD from other conditions and be familiar with how co-occurring conditions may manifest in the context of ASD. ASD symptoms present differently across development, underscoring the need for training about typical developmental expectations for youth. Periodic reevaluations throughout development are also important because support needs for individuals with autism change over time.

Keywords: Autism; Autism diagnosis; Differential diagnosis; Neurodevelopmental disorders.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Autism Spectrum Disorder* / diagnosis
  • Autistic Disorder* / diagnosis
  • Diagnosis, Differential
  • Humans
  • Neurodevelopmental Disorders* / diagnosis