[Research Progress in the Roles of Sympathetic Nervous System in Liver Cirrhosis and Its Complications]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2024 Feb;46(1):128-134. doi: 10.3881/j.issn.1000-503X.15876.
[Article in Chinese]

Abstract

The sympathetic nervous system(SNS)plays a pivotal role in maintaining organ homeostasis and the pathogenesis of various ailments.Studies have unveiled a profound interconnection between sympathetic nerves and the development of liver cirrhosis,cirrhotic cardiomyopathy,and hepatorenal syndrome.Therefore,researchers have proposed SNS as a candidate therapeutic target for liver-related disorders.This article reviewed the research progress of sympathetic nerves in liver cirrhosis,cirrhotic cardiomyopathy,and hepatorenal syndrome,aiming to enrich the knowledge about the roles of sympathetic nerves in cirrhosis and its complications and provide new ideas for the treatment of liver cirrhosis and its complications.

交感神经系统(SNS)在维持器官正常功能和疾病发生发展中起着重要作用。目前研究发现交感神经与肝硬化、肝硬化心肌病和肝肾综合征(HRS)的发生发展密切相关,SNS也许可作为肝脏相关疾病的治疗靶点。为了深入理解交感神经在肝硬化及其并发症的作用,本文综述了交感神经在肝硬化、肝硬化心肌病和HRS中的作用研究进展,以此为治疗肝硬化及其并发症提供新思路。.

Keywords: liver cirrhosis; mechanism; progress; sympathetic nervous system.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Cardiomyopathies*
  • Hepatorenal Syndrome*
  • Homeostasis
  • Humans
  • Liver Cirrhosis
  • Sympathetic Nervous System