Angiolymphoid Hyperplasia with Eosinophilia of the External Auditory Canal

Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):1037-1039. doi: 10.1007/s12070-023-04100-w. Epub 2023 Jul 25.

Abstract

Angiolymphoid hyperplasia with eosinophilia is a rare, benign, vaso-proliferative disease with a dense eosinophilic inflammatory infiltrate seen in the intradermal or subcutaneous region. It is also termed an epitheloid hemangioma, and it mostly affects females rather than males. It is seen as reddish to brown, fleshy, proliferative, papular, or nodular lesion affecting the head and neck region, most commonly the auricular and periauricular regions. The aetiology is unknown, but the most likely causes are trauma, infection, and hyperestrogenic condition like pregnancy or the use of oral contraceptive agents. It usually measures about 2-3 cm in size. It should be differentiated from Kimura disease, which is characterized by chronic inflammation and large subcutaneous nodules in the head and neck region. Here is a rare case report of angiolymphoid hyperplasia in a middle-aged male patient involving the external auditory canal of the left ear.

Keywords: Angiolymphoid hyperplasia; Auricular region; Eosinophilia; Epitheloid hemangioma; Kimura.