UCP1 and CKB are parallel players in BAT

Cell Metab. 2024 Mar 5;36(3):459-460. doi: 10.1016/j.cmet.2024.01.016.


It is generally believed that the contributions of the UCP1-independent thermogenic pathways are secondary to UCP1-mediated thermogenesis in BAT. Now, Rahbani et al. demonstrate in vivo that adaptive thermogenesis in brown adipose tissue is regulated by UCP1 and CKB in parallel.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adipose Tissue, Brown*
  • Thermogenesis*