Pregabalin Adjuventia Helped Risperidone-Induced Extrapyramidal Syndrome and Augmented Antipsychotic Response in an Adolescent with Schizophrenia

Psychopharmacol Bull. 2024 Mar 4;54(1):40-42.
  • PMID: 38449476
  • PMCID: PMC10913867 (available on )

Abstract

Here, authors report on an interesting case of early-onset of schizophrenia where adjunctive pregabalin alleviated risperidone-induced pseudoparkinsonism, helped with insomnia and agitation and boosted antipsychotic response with great tolerability. We wager that gabapentenoids can be a viable option in the niche of psychopharmacotherapy of schizophrenia in CAP population.

Keywords: EPS; adolescence; pregabalin; schizophrenia.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antipsychotic Agents* / adverse effects
  • Humans
  • Pregabalin / therapeutic use
  • Risperidone / adverse effects
  • Schizophrenia* / drug therapy

Substances

  • Risperidone
  • Antipsychotic Agents
  • Pregabalin