The many enigmas of nicotine

Adv Pharmacol. 2024:99:327-354. doi: 10.1016/bs.apha.2023.08.001. Epub 2023 Oct 17.

Abstract

This review discusses the diverse effects of nicotine on the various nicotinic acetylcholine receptors of the central and peripheral nervous system and how those effects may promote the usage and addiction to tobacco products.

Keywords: Addiction; Dependence; Desensitization; Dopamine; Nicotine; Smoking.

Publication types

  • Review

MeSH terms

  • Humans
  • Nicotine / pharmacology
  • Receptors, Nicotinic*
  • Tobacco Use Disorder*

Substances

  • Nicotine
  • Receptors, Nicotinic