Waxy papules, infiltrated alopecic plaques, and shin ichthyosis

Int J Dermatol. 2024 Mar 19. doi: 10.1111/ijd.17087. Online ahead of print.

Abstract

A 38-year-old male presented with waxy papules, plaques over the neck and extremities, and ichthyotic scales over the lower limbs. Skin biopsy revealed a dense medium-sized lymphocytic infiltrate in the dermis, with perifollicular accentuation and focal exocytosis into the follicular epithelium with strong positivity for CD 3, 4, and 5. Considering the clinicopathological correlation, a diagnosis of follicular mycosis fungoides (FMF) was made. It is a variant of classic mycosis fungoides (MF) where atypical cells invade the follicular epithelium.

Keywords: cutaneous T-cell lymphoma; dermatopathology; mycosis fungoides.