Post Trauma Acinetobacter Baumanii Meningitis Treatment Approach

Ulus Travma Acil Cerrahi Derg. 2024 Mar;30(3):221-225. doi: 10.14744/tjtes.2024.65051.


A. baumannii, which is said to be associated with nosocomial infections is considered a significant mortality risk if not adequately addressed. A. baumannii infections typically occur in the aftermath of surgery or trauma. Our patient developed complicated A. baumannii meningitis with lateral ventriculitis and a lumbar abscess post surgery after suffering from a fall. The patient was treated with a 21-day regimen of intrathecally administered colistin and polymyxin B. Following this therapeutic period, the patient's condition improved, ultimately leading to successful recovery and subsequent discharge. This case report serves to highlight the ability of intrathecal administration of antibiotics, that normally have limited potential of crossing the blood-brain-barrier, to lead to improved survival outcomes in multi-drug resistant nosocomial meningitis.

Publication types

  • Case Reports

MeSH terms

  • Acinetobacter Infections* / drug therapy
  • Acinetobacter baumannii*
  • Anti-Bacterial Agents / therapeutic use
  • Colistin / therapeutic use
  • Humans
  • Meningitis, Bacterial* / drug therapy


  • Anti-Bacterial Agents
  • Colistin