The rationale for bladder washouts in children with neurogenic bladder

Neurourol Urodyn. 2024 Apr;43(4):1019-1024. doi: 10.1002/nau.25450. Epub 2024 Mar 22.

Abstract

Children with a neurogenic bladder are at risk of developing recurrent urinary tract infections and long-term kidney failure. Due to an altered lower urinary tract, children may be overtreated for simple bacteriuria or undertreated for a potentially severe urinary tract infection. This group of patients represent high users of healthcare, and are at risk of colonization and development of antibiotic resistance. Bladder washouts with non-antibiotic electrochemically activated solutions are a potential new prophylactic option for patients with bladder dysfunction when clean intermittent catheterization has resulted in chronic bacteriuria.

Keywords: antibiotic resistance; bladder washouts; neurogenic bladder; urinary tract infections.

MeSH terms

  • Bacteriuria*
  • Child
  • Humans
  • Intermittent Urethral Catheterization*
  • Urinary Bladder
  • Urinary Bladder, Neurogenic* / etiology
  • Urinary Catheterization / adverse effects
  • Urinary Tract Infections* / etiology