Olfactory information processing viewed through mitral and tufted cell-specific channels

Tatsumi Hirata

doi:10.3389/fncir.2024.1382626

Olfactory information processing viewed through mitral and tufted cell-specific channels

Front Neural Circuits. 2024 Mar 8:18:1382626. doi: 10.3389/fncir.2024.1382626. eCollection 2024.

Author

Tatsumi Hirata¹

Affiliation

¹ Brain Function Laboratory, National Institute of Genetics, SOKENDAI, Mishima, Japan.

Abstract

Parallel processing is a fundamental strategy of sensory coding. Through this processing, unique and distinct features of sensations are computed and projected to the central targets. This review proposes that mitral and tufted cells, which are the second-order projection neurons in the olfactory bulb, contribute to parallel processing within the olfactory system. Based on anatomical and functional evidence, I discuss potential features that could be conveyed through the unique channel formed by these neurons.

Keywords: mitral cell; mouse; neurogenic tagging; olfactory system; parallel processing; tufted cell.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Cognition
Interneurons
Neurons* / physiology
Olfactory Bulb / physiology
Smell* / physiology

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This article was supported by the MEXT/JSPS KAKENHI Grants (20H03345, 23H02581) and IU-REAL Collaborative Research Grant.