Challenges and Opportunities in Valvular Heart Disease: From Molecular Mechanisms to the Community

Elena Aikawa; Mark C Blaser; Sasha A Singh; Robert A Levine; Magdi H Yacoub

doi:10.1161/ATVBAHA.123.319563

Challenges and Opportunities in Valvular Heart Disease: From Molecular Mechanisms to the Community

Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):763-767. doi: 10.1161/ATVBAHA.123.319563. Epub 2024 Mar 27.

Authors

Elena Aikawa^{1

2}, Mark C Blaser¹, Sasha A Singh¹, Robert A Levine³, Magdi H Yacoub⁴

Affiliations

¹ Center for Interdisciplinary Cardiovascular Sciences, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital (E.A., M.C.B., S.A.S.), Harvard Medical School, Boston.
² Center for Excellence in Vascular Biology, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital (E.A.), Harvard Medical School, Boston.
³ Division of Cardiology, Cardiac Ultrasound Laboratory, Massachusetts General Hospital (R.A.L.), Harvard Medical School, Boston.
⁴ Imperial College London, United Kingdom (M.H.Y.).

PMID: 38536897
PMCID: PMC10977651 (available on 2025-04-01)
DOI: 10.1161/ATVBAHA.123.319563

Abstract

Keywords: aortic valve stenosis; drug discovery; heart valve prosthesis; heart valves; mitral valve regurgitation; rheumatic heart disease; tissue engineering.

MeSH terms

Heart Valve Diseases* / genetics
Heart Valve Diseases* / therapy
Heart Valve Prosthesis*
Humans
Mitral Valve Insufficiency*

Abstract

MeSH terms

Grants and funding