Neovaginal cancer after sigmoid vaginoplasty: Implications for postoperative cancer surveillance

JPRAS Open. 2024 Mar 7:40:170-174. doi: 10.1016/j.jpra.2024.03.002. eCollection 2024 Jun.

Abstract

Background: Intestinal vaginoplasty can be performed as vaginal reconstruction procedure. Aa pedicled intestinal segment is isolated and transferred to the (neo)vaginal cavity to form the neovaginal lining.

Case: A 38-year old patient with Fanconi anemia and congenital vaginal absence, who underwent sigmoid vaginoplasty at the age of one, visited the outpatient clinic with a palpable neovaginal mass. At MRI examination, a neovaginal tumor was observed of approximately 25 × 10 mm without lymphadenopathy, which turned out to be a mucinous adenocarcinoma (T3N0M0). She underwent excision of the total mesocolon, including the sigmoid neovagina, coloanal anastomosis and anus.

Summary and conclusion: Postoperative cancer surveillance seems justified after sigmoid vaginoplasty, even more so in patients with a (genetically) high risk of developing cancer and/or with a history of malignancy.

Keywords: Cancer; Intestinal vaginoplasty; Neovagina; Sigmoid vaginoplasty; Transgender.

Publication types

  • Case Reports