Role of Hematological Indices as Predictors of Systemic Inflammation in Dermatology

Sanmitra Aiholli; Keshavmurthy A Adya; Arun C Inamadar

doi:10.4103/idoj.idoj_189_23

Role of Hematological Indices as Predictors of Systemic Inflammation in Dermatology

Indian Dermatol Online J. 2023 Nov 24;15(2):188-195. doi: 10.4103/idoj.idoj_189_23. eCollection 2024 Mar-Apr.

Authors

Sanmitra Aiholli¹, Keshavmurthy A Adya¹, Arun C Inamadar¹

Affiliation

¹ Department of Dermatology, Venereology and Leprosy, Shri B M Patil Medical College, Hospital and Research Center, BLDE (Deemed to be University), Vijayapur, Karnataka, India.

Abstract

Hematological indices have long been used in a variety of conditions as indicators of systemic inflammation. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are inexpensive tools in predicting severity and disease activity in acute coronary syndrome, malignancy, coronavirus disease 2019 (COVID-19) illness, and other autoimmune conditions. Evidence suggests that such hematological indices can be used in various dermatoses as predictors of systemic inflammation, to assess the severity of the disease, prognosis, and treatment response.

Keywords: Hematological biomarkers; hematological indices; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; systemic inflammation.

Publication types

Review