Patient-physician sex concordance and outcomes in cardiovascular disease: a systematic review

Eur Heart J. 2024 May 7;45(17):1505-1511. doi: 10.1093/eurheartj/ehae121.


The sex disparity in outcomes of patients with cardiovascular disease is well-described and has persisted across recent decades. While there have been several proposed mechanisms to explain this disparity, there are limited data on female patient-physician sex concordance and its association with outcomes. The authors review the existing literature on the relationship between patient-physician sex concordance and clinical outcomes in patients with cardiovascular disease, the evidence of a benefit in clinical outcomes with female patient-physician sex concordance, and the possible drivers of such a benefit and highlight directions for future study.

Keywords: Cardiovascular disease; Clinical outcomes; Patient–physician sex concordance; Sex concordance; Sex disparity; Women’s health.

Publication types

  • Systematic Review
  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cardiovascular Diseases*
  • Female
  • Humans
  • Male
  • Physician-Patient Relations*
  • Sex Factors
  • Treatment Outcome