Successful and Rapid Reduction in Neurosedative and Analgesic Medications in Complex Infants with Severe Bronchopulmonary Dysplasia After Tracheostomy Placement: Experience with 24-hour Propofol Infusions

J Pediatr. 2024 Jul:270:114040. doi: 10.1016/j.jpeds.2024.114040. Epub 2024 Mar 28.

Abstract

Infants with severe bronchopulmonary dysplasia may require high doses of neurosedative medications to ensure pain control and stability following tracheostomy placement. Subsequent weaning of these medications safely and rapidly is a challenge. We describe a 24-hour propofol infusion to reduce neurosedative medications in 3 high-risk infants following tracheostomy placement.

Publication types

  • Case Reports

MeSH terms

  • Analgesics / administration & dosage
  • Analgesics / therapeutic use
  • Anesthetics, Intravenous / administration & dosage
  • Bronchopulmonary Dysplasia*
  • Female
  • Humans
  • Hypnotics and Sedatives / administration & dosage
  • Infant
  • Infant, Newborn
  • Infusions, Intravenous
  • Male
  • Postoperative Pain / drug therapy
  • Propofol* / administration & dosage
  • Tracheostomy* / methods

Substances

  • Propofol
  • Hypnotics and Sedatives
  • Analgesics
  • Anesthetics, Intravenous