With an increasing understanding of growth hormone deficiency, there has been a growing emphasis on the management of transition growth hormone deficiency (TGHD) in clinical practice. The inadequate diagnosis and treatment of TGHD have been a major clinical concern, leading to the development of relevant guidelines and consensus internationally. This article summarizes the evaluation, diagnosis, treatment, and clinical challenges of TGHD based on these guidelines, consensus, and existing clinical studies, aiming to optimize and further improve the clinical diagnosis, treatment, and management of TGHD.
随着对生长激素缺乏症认识的不断深入，临床逐渐重视过渡期生长激素缺乏症（transition growth hormone deficiency, TGHD）的管理。TGHD诊治不足是主要的临床痛点，为规范TGHD诊治，国内外已发布了相关指南/共识。该文结合指南/共识和现有临床研究，总结了TGHD的评估、诊断、治疗和临床挑战，以期优化和进一步改善TGHD临床诊治和管理。.
Keywords: Disease management; Growth hormone deficiency; Recombinant human growth hormone; Transition period.