Paraneoplastic Syndrome Case Presented As Nystagmus and Ataxia

Abstract

The incidence of paraneoplastic syndrome (PNS) is on the rise, attributed to the growing detection of antibody modalities in both the serum and cerebrospinal fluid (CSF). PNS can occur as different neurological symptoms. The revised guidelines streamline the diagnostic approach but identifying PNS still requires the detection of neurological manifestations concurrent with cancer, along with the presence of specific PNS autoantibodies.

Keywords: cancer complication; cerebellar degene; cerebellar-ataxia; downbeat nystagmus; malignancy – endometrial carcinoma – uterine bleeding – serous carcinoma; paraneoplastic antibodies; paraneoplastic cerebellitis; paraneoplastic neurological syndromes; uterine cancer; vertigo.