WormBase 2024: status and transitioning to Alliance infrastructure

Genetics. 2024 Apr 4:iyae050. doi: 10.1093/genetics/iyae050. Online ahead of print.

Abstract

WormBase has been the major repository and knowledgebase of information about the genome and genetics of C. elegans and other nematodes of experimental interest for over two decades. We have three goals: to keep current with the fast-paced C. elegans research, to provide better integration with other resources, and to be sustainable. Here we discuss the current state of WormBase as well as progress and plans for moving core WormBase infrastructure to the Alliance of Genome Resources (the Alliance). As an Alliance member, WormBase will continue to interact with the C. elegans community, develop new features as needed, and curate key information from the literature and large-scale projects.

Keywords: Caenorhabditis elegans; Global Core Biodata Resource; model organism; bioinformatics tools; disease models; genome annotation; knowledgebase; software.