Vertical Transmission of Hepatitis C Virus Among Women With a History of Injection Opioid Use

Clin Infect Dis. 2024 Sep 26;79(3):701-704. doi: 10.1093/cid/ciae177.

Abstract

We evaluated vertical transmission and linkage to care in women with hepatitis C virus (HCV) and history of injection drug use employing co-localized testing and treatment. Transmission occurred in 1 of 23 infants, with mother-infant genetic distance of 1.26%. Rates for infant testing, maternal linkage, and cure were 77%, 52%, and 100%, respectively.

Keywords: hepatitis C; phylogenetic analysis; pregnancy; vertical transmission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Hepacivirus / genetics
  • Hepatitis C* / drug therapy
  • Hepatitis C* / epidemiology
  • Hepatitis C* / transmission
  • Humans
  • Infant
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnancy Complications, Infectious / virology
  • Substance Abuse, Intravenous* / complications
  • Young Adult

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