Evidence from whole genome sequencing of aerosol transmission of SARS-CoV-2 almost 5 hours after hospital room turnover

Am J Infect Control. 2024 Jul;52(7):849-851. doi: 10.1016/j.ajic.2024.04.003. Epub 2024 Apr 5.

Abstract

Experimental evidence suggests that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) remains viable within aerosols with a half-life of approximately 3 hours; however, it remains unclear how long airborne SARS-CoV-2 can transmit infection. Whole genome sequencing during an outbreak suggested in-room transmission of SARS-CoV-2 to two patients admitted nearly 2 and 5 hours, respectively, after discharge of an asymptomatic infected patient. These findings suggest that airborne SARS-CoV-2 may transmit infection for over 4 hours, even in a hospital setting.

Keywords: COVID-19; Outbreak.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aerosols
  • Air Microbiology
  • COVID-19* / epidemiology
  • COVID-19* / transmission
  • COVID-19* / virology
  • Cross Infection / transmission
  • Cross Infection / virology
  • Genome, Viral
  • Humans
  • Male
  • Middle Aged
  • SARS-CoV-2* / genetics
  • Time Factors
  • Whole Genome Sequencing*

Substances

  • Aerosols