Seizures as presentation of shunt malfunction: tertiary paediatric neurosurgery experience

Aimee Goel; Vesta S Najmi; Katie Herbert; Amy Drew; Desiderio Rodrigues; Fardad T Afshari

doi:10.1007/s00381-024-06388-7

Seizures as presentation of shunt malfunction: tertiary paediatric neurosurgery experience

Childs Nerv Syst. 2024 Apr 8. doi: 10.1007/s00381-024-06388-7. Online ahead of print.

Authors

Aimee Goel¹, Vesta S Najmi¹, Katie Herbert¹, Amy Drew¹, Desiderio Rodrigues¹, Fardad T Afshari²

Affiliations

¹ Department of Neurosurgery, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK.
² Department of Neurosurgery, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. afsharifardad@googlemail.com.

PMID: 38587624
DOI: 10.1007/s00381-024-06388-7

Abstract

Aim: Patients with a background of cerebrospinal fluid (CSF)-diverting shunts are frequently investigated for shunt malfunction when presenting with seizures. However, there is very limited evidence in the literature regarding the association of seizures and shunt malfunction. We sought to determine the incidence of shunt malfunction in our cohort of shunted paediatric patients presenting with seizures, and the utility of seizures as a marker of shunt malfunction.

Methods: We retrospectively identified all shunted patients presenting with seizures, as well as all patients undergoing shunt revision following a presentation with seizures from our hospital database over a 14-year period from 2009 to 2023. Data gathered included demographics, de novo seizures or change in pattern of seizures, the aetiology of hydrocephalus and the segment of shunt requiring revision. Exclusion criteria included infected cases requiring shunt externalisation. A literature review of all papers discussing seizures as a presentation of shunt malfunction was also carried out.

Results: Overall, over a 14-year period of study, 338 shunted patients presented with seizures and were referred as suspected shunt malfunction with 10 having confirmed shunt malfunction requiring revision (2.9%). This group represented 6.2% of 161 cases of shunt revision carried out during the 14-year period of study. Post-haemorrhagic hydrocephalus secondary to prematurity was the commonest aetiology of shunted hydrocephalus presenting with seizures. Out of 10 patients presenting with seizures with shunt malfunction, 4 presented with de novo seizures, while 6 presented with a change in seizure pattern or frequency in already known epileptic patients. Shunt revision surgeries included 5 distal catheter, 2 proximal catheter, 1 proximal catheter-valve, 1 valve only and 1 case of whole shunt change.

Conclusion: Our data supports that seizures are rare manifestation of shunt malfunction and can present either de novo or with a change in seizure frequency in already-known epileptic patients.

Keywords: Epilepsy; Hydrocephalus; Seizure; Shunt malfunction.