Sclerosing angiomatoid nodular transformation (SANT) of the spleen can be safely diagnosed by a core percutaneous ultrasound-guided biopsy

Rev Esp Enferm Dig. 2025 Apr;117(4):225-227. doi: 10.17235/reed.2024.10373/2024.

Abstract

Sclerosing angiomatoid nodular transformation (SANT) is a rare benign lesion of the spleen. SANT cannot be distinguished from other benign or malignant splenic tumors based on imaging findings. So, diagnosis relies on histopathologic examination. Although splenectomy is frequently considered as an option, core needle biopsy tissue analysis is safe and accurate to avoid surgery.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Large-Core Needle
  • Female
  • Histiocytoma, Benign Fibrous* / diagnostic imaging
  • Histiocytoma, Benign Fibrous* / pathology
  • Humans
  • Image-Guided Biopsy* / methods
  • Middle Aged
  • Spleen* / diagnostic imaging
  • Spleen* / pathology
  • Splenectomy
  • Splenic Diseases* / diagnostic imaging
  • Splenic Diseases* / pathology
  • Splenic Neoplasms* / diagnostic imaging
  • Splenic Neoplasms* / pathology
  • Ultrasonography, Interventional