68Ga-DOTATATE and 18F-FDG PET Imaging of a Rare Chordoid Meningioma With Intracranial Recurrence and Extracranial Metastases

Mathew V Smith; Harrison J Lang; Kliment Donev; Bernard R Bendok; Ming Yang

doi:10.1097/RLU.0000000000005237

68Ga-DOTATATE and 18F-FDG PET Imaging of a Rare Chordoid Meningioma With Intracranial Recurrence and Extracranial Metastases

Clin Nucl Med. 2024 Apr 5. doi: 10.1097/RLU.0000000000005237. Online ahead of print.

Authors

Mathew V Smith¹, Harrison J Lang¹, Kliment Donev², Bernard R Bendok³, Ming Yang¹

Affiliations

¹ From the Department of Radiology, Mayo Clinic Arizona.
² Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona.
³ Department of Neurological Surgery, Mayo Clinic Arizona.

PMID: 38598744
DOI: 10.1097/RLU.0000000000005237

Abstract

Chordoid meningiomas, rare meningioma variants, are characterized by their histopathological features and clinical behavior resembling that of other chondroid/myxoid neoplasms. We present a case of pathology-proven chordoid meningioma imaged with both 68Ga-DOTATATE and 18F-FDG PET images during a complicated postoperative course with multiple episodes of local recurrence and, ultimately, extracranial metastasis. This case underscores the aggressive behavior of chordoid meningiomas while highlighting how molecular imaging plays an important role in clinical monitoring and guidance of management.