Ventricular Thrombus Formation Caused by Subendomyocardial Inflammation in Eosinophilic Granulomatosis With Polyangiitis

JACC Case Rep. 2024 Apr 4;29(10):102321. doi: 10.1016/j.jaccas.2024.102321. eCollection 2024 May 15.

Abstract

Cardiac involvement of eosinophilic granulomatosis with polyangiitis is a rare but life-threatening complication. We present a case of eosinophilic granulomatosis with polyangiitis with moderately impaired ventricular function forming a ventricular thrombus. Pathological assessment of endomyocardial biopsy specimen revealed aggregated eosinophils in the subendocardium, suggesting ventricular endothelial damage leading to thrombus formation.

Keywords: cardiac magnetic resonance; endomyocardial biopsy; eosinophilic granulomatous with polyangiitis; ventricular thrombus.

Publication types

  • Case Reports