Spontaneous Remission in Adult Acute Leukemia

Cancer. 1985 Sep 1;56(5):1187-90. doi: 10.1002/1097-0142(19850901)56:5<1187::aid-cncr2820560536>3.0.co;2-o.

Abstract

A spontaneous complete remission of 34 months' duration was observed in an adult patient with acute myeloblastic leukemia. The remission occurred after a severe febrile pneumonia, which was treated with leukocyte transfusions. At relapse, chromosomal abnormalities reappeared slowly. Such spontaneous complete remissions, almost always associated with bacterial infections and blood transfusions, are extremely rare, and are usually of short duration. Previous cases are summarized, and the role of etiologic factors, including those related to the leukemic proliferation, are discussed.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Blood Transfusion
  • Bone Marrow / pathology
  • Humans
  • Leukemia, Myeloid, Acute / blood
  • Leukemia, Myeloid, Acute / complications
  • Leukemia, Myeloid, Acute / pathology*
  • Leukocyte Transfusion
  • Male
  • Middle Aged
  • Neoplasm Regression, Spontaneous*
  • Pneumonia / complications
  • Pneumonia / therapy
  • Recurrence

Substances

  • Anti-Bacterial Agents