Modified three-layer vesicourethral reconstruction in robot-assisted radical prostatectomy can change cystography pattern and improve early recovery of continence

J Surg Oncol. 2024 Jun;129(7):1332-1340. doi: 10.1002/jso.27636. Epub 2024 Apr 12.

Abstract

Background and objectives: To determine early continence outcomes after three-layer vesicourethral reconstruction during robot-assisted radical prostatectomy (RARP) and the role of postoperative cystography pattern.

Methods: Between May 2015 and January 2019, a total of 170 consecutive patients with localized prostate cancer who underwent RARP, were divided into one- and three-layer groups based on the method of vesicourethral reconstruction. Continent status, preoperative, intraoperative, postoperative, clinicopathological variables, and cystography parameters were analyzed. The patients were followed up for at least 12 months.

Results: Of the 170 consecutive patients, 85 with one-layer vesicourethral anastomosis, and 85 with three-layer reconstruction. The continence rates immediately after catheter removal, 4, 12, and 24 weeks after RARP were 47.1%, 75.3%, 92.9%, and 98.8% in the three-layer group; compared to 15.3%, 60%, 78.8%, and 90.6% in the one-layer group, respectively. In the multivariate analysis, three-layer reconstruction was the only independent variable with a 42% risk reduction of postprostatectomy incontinence (hazard ratio (HR): 0.58, 95% confidence interval (CI) = 0.42-0.80, p = 0.001). Cystography in the three-layer group revealed less anastomotic leakage, less sharp bladder neck angle, and higher bladder neck level category.

Conclusions: Three-layer anatomical reconstruction demonstrated promising early continence outcomes, and postoperative cystography revealed a specific pattern more associated with continence.

Keywords: cystography; prostate neoplasms; prostatectomy; robotic surgical procedures; urinary incontinence.

MeSH terms

  • Aged
  • Cystography* / methods
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Plastic Surgery Procedures* / methods
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Prognosis
  • Prostatectomy* / methods
  • Prostatic Neoplasms* / diagnostic imaging
  • Prostatic Neoplasms* / surgery
  • Recovery of Function
  • Retrospective Studies
  • Robotic Surgical Procedures* / methods
  • Urethra* / diagnostic imaging
  • Urethra* / surgery
  • Urinary Bladder* / diagnostic imaging
  • Urinary Bladder* / surgery
  • Urinary Incontinence* / etiology
  • Urinary Incontinence* / prevention & control