Extragonadal Germ Cell Tumor with Hepatic Infiltration in a Child: Aberrant Somatostatin Receptors and the Diagnostic Conundrum

Nitin James Peters; Saswati Behera; Parikshaa Gupta; Richa Jain; Harmandeep Singh; Renu Madan; Jai Kumar Mahajan

doi:10.4103/jiaps.jiaps_167_23

Extragonadal Germ Cell Tumor with Hepatic Infiltration in a Child: Aberrant Somatostatin Receptors and the Diagnostic Conundrum

J Indian Assoc Pediatr Surg. 2024 Mar-Apr;29(2):162-164. doi: 10.4103/jiaps.jiaps_167_23. Epub 2024 Mar 4.

Authors

Nitin James Peters¹, Saswati Behera¹, Parikshaa Gupta², Richa Jain³, Harmandeep Singh⁴, Renu Madan⁵, Jai Kumar Mahajan¹

Affiliations

¹ Department of Pediatric Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
² Department of Cytology and Gynae Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
³ Department of Pediatrics, Pediatric Hemato-Oncology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
⁴ Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
⁵ Department of Radiation Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

Extragonadal germ cell tumors (GCTs) are challenging to diagnose. We present a case of suprarenal GCT, with hepatic infiltration where differential diagnosis included neuroblastoma and hepatoblastoma. The positive positron emission tomography scan further obfuscated the situation. The diagnosis was clinched by fine-needle aspiration cytology and cell block immunohistochemistry.

Keywords: DOTATET positron emission tomography scan; SALL4 IHC; extragonadal germ cell tumor; fine-needle aspiration cytology; somatostatin.

Publication types

Case Reports