Transient activation of retinopathy of prematurity secondary to erythrocyte suspension transfusion

Rom J Ophthalmol. 2024 Jan-Mar;68(1):57-59. doi: 10.22336/rjo.2024.11.

Abstract

Retinopathy of prematurity (ROP) is a serious retinal vascular disorder that needs prompt diagnosis, and treatment to prevent undesired visual outcomes. Due to its shorter period of disease progression, it is important to be hasty in treating ROP. Erythrocyte suspension (ES) aggravates the progression of ROP. However, this progression may be transient as in the present case reports. This case report aimed to present two cases that developed type 1 ROP after erythrocyte suspension transfusion. Clinical findings of the patients were resolved within a few days without any intervention. Premature infants receiving ES treatment can be observed for 24-48 hours, and the treatment can be planned after determining the persistence of the plus sign. Abbreviations: ES = Erythrocyte suspension, ROP = Retinopathy of prematurity, NICU = neonatal intensive care unit.

Keywords: erythrocyte suspension; plus sign; retinopathy of prematurity; transfusion; transient activation.

Publication types

  • Case Reports

MeSH terms

  • Erythrocytes
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Retinopathy of Prematurity* / diagnosis
  • Retinopathy of Prematurity* / etiology