Hyaline cartilage at the portal plate and gallbladder in biliary atresia

Sangamitra Rajasekaran; Hari Neupane; Monika Bawa; Uma Nahar Saikia; Sadhna Lal; Suvradeep Mitra

doi:10.4322/acr.2024.481

Hyaline cartilage at the portal plate and gallbladder in biliary atresia

Autops Case Rep. 2024 Apr 4:14:e2024481. doi: 10.4322/acr.2024.481. eCollection 2024.

Authors

Sangamitra Rajasekaran¹, Hari Neupane¹, Monika Bawa², Uma Nahar Saikia¹, Sadhna Lal³, Suvradeep Mitra¹

Affiliations

¹ Post Graduate Institute of Medical Education and Research (PGIMER), Department of Histopathology, Chandigarh, India.
² Post Graduate Institute of Medical Education and Research (PGIMER), Department of Pediatric Surgery, Chandigarh, India.
³ Post Graduate Institute of Medical Education and Research (PGIMER), Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Chandigarh, India.

Abstract

Biliary atresia (BA) is a fibro-obliterative cholestatic disease of infancy. The presence of cartilage in the resected tissue is an uncommon finding. We documented the presence of both mature and immature hyaline cartilage in the portal plate and the wall of the gallbladder in a 2-month-old girl infant with BA who had undergone Kasai portoenterostomy. The presence of cartilage could be part of a heterotopia or an uncommon connective tissue metaplasia. The presence of immature cartilage with the merging of the perichondrium with the soft tissue highlights a metaplastic etiology in the index case.

Keywords: Biliary atresia; Gallbladder; Hyaline cartilage; Metaplasia; Portal plate.

Publication types

Case Reports