Research and application progress of microbial β-mannanases: a mini-review

World J Microbiol Biotechnol. 2024 Apr 17;40(6):169. doi: 10.1007/s11274-024-03985-1.

Abstract

Mannan is a predominant constituent of cork hemicellulose and is widely distributed in various plant tissues. β-Mannanase is the principal mannan-degrading enzyme, which breaks down the β-1,4-linked mannosidic bonds in mannans in an endo-acting manner. Microorganisms are a valuable source of β-mannanase, which exhibits catalytic activity in a wide range of pH and temperature, making it highly versatile and applicable in pharmaceuticals, feed, paper pulping, biorefinery, and other industries. Here, the origin, classification, enzymatic properties, molecular modification, immobilization, and practical applications of microbial β-mannanases are reviewed, the future research directions for microbial β-mannanases are also outlined.

Keywords: Application; Catalytic mechanism; Enzymatic property; Microbial β-mannanase; Molecular modification.

Publication types

  • Review

MeSH terms

  • Mannans*
  • Temperature
  • beta-Mannosidase* / genetics

Substances

  • Mannans
  • beta-Mannosidase